OpenMacGrid Project Proposal Form
By dgohara at Wed, Jan 31 2007 7:48am
To submit a project proposal for OpenMacGrid you need to be a registered MacResearch user. Registration is free. When you are registered, login and fill out the form below. Once MacResearch receives your submission we will review it and notify you of the status of your project. Please fill in all fields.
If you'd prefer to simply upload a PDF document with all of the relevant information, just use the file upload button at the bottom and click submit. Be sure your entry has ALL of the information requested in the form.



Comments
Project proposal form
Richard J. Feldmann
Global Determinants, Inc.
Derwood, Maryland
I can't get to the proposal form.
Proposal forms
There was some issue with the transition to the new site, we are working on getting the form back. Please contact one of us by email with the proposal in the meantime.
Shift
The interactions between biomolecules (proteins, nucleic acids, small organic molecules) are the driving force for every biological function. Virtually all diseases can be traced back to misregulation of these interactions. For example, breast cancer, estimated to affect 1 in 8 American women, is linked to the over-activation of the EGF receptors (a membrane protein) in ~30% of the patients. The EGF receptor is then a clear therapeutic "target" for the development of a drug that will interact with it and "restore" a proper non-pathological state. More generally, many of the FDA-approved drugs are small molecules that can bind and alter (inhibit or enhance) the functional effectiveness of the corresponding therapeutic protein targets.
Thanks for the interesting
Thanks for the interesting article
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It's also much easier for
It's also much easier for those at home to contribute to the OpenMacGrid project. No software installation is needed. The only requirement is that they run Mac OS X 10.4 or later. Some settings must be made in System Preferences, but that's all. A dedicated Dashboard widget is available so that users can monitor activity on the grid.
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